Clinical Case Database / Category: Case Based Discussion

The short synacthen test

Publication details

Jaimini Cegla, Professor Graham R Williams
Foundation Years Journal, volume 2, issue 7, p.306 (123Doc Education, London, September 2008)


A 32-year-old man presented to the Accident and Emergency department with a 3-day history of persistent vomiting. He had felt increasingly tired with weight loss over the previous few months despite returning recently from holiday in Spain. He reported that his clothes were looser than usual and his suntan had persisted, but did not complain of additional symptoms. In particular, his bowel habit was normal and he had not experienced abdominal pain. His previous medical history was unremarkable and the patient was taking no medications. There was a family history of hypothyroidism affecting his mother and sister.

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Jaimini Cegla

Department of Metabolic Medicine
Hammersmith Hospital
Imperial College Healthcare NHS Trust
Du Cane Road, London W12 0NN

Professor Graham R Williams (Corresponding author)

Molecular Endocrinology Group
MRC Clinical Sciences Centre
Hammersmith Hospital
Du Cane Road, London W12 0NN


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T​he Foundation Years Clinical Cases Database is​ a selection of 600 peer-reviewed clinical cases in the field of patient safety and clinical practice, specifically focused on the clinical information needs of junior doctors, based around the Foundation Year Curriculum programme (MMC). The cases have been chosen to align with the Foundation Year Curriculum.

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