Clinical Case Database / Category: Case Based Discussion

Tests for Helicobacter Pylori

Publication details

Simon J. Leedham, Dawn L. Leeedham
Foundation Years Journal, volume 1, issue 3, p.100 (123Doc Education, London, June 2007)


A 37-year-old man presents to the GP surgery with recurrent episodes of dyspepsia unresponsive to self-medication with over-the-counter Gaviscon and ranitidine. On direct questioning there is no history of weight loss, vomiting, haematemesis or dysphagia. How would you proceed to investigate this patient?

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Simon J. Leedham

Gastroenterology SpR and Clinical Research Fellow
Cancer Research UK

Dawn L. Leeedham

GP registrar
Petersfild Surgery
Harold Hill
Essex Hepatology Audit


1.  Shah, R. Dyspepsia and Helicobacter pylori. BMJ 334, 41-43 (2007).

2.  National Institute for Health and Clinical Excellence. Managing dyspepsia in adults in primary care. (2004 - updated 2005).

3.  Elwyn, G. et al. Which test is best for Helicobacter pylori? A costeffectiveness model using decision analysis. Br J Gen Pract 57, 401-403 (2007).

4.  Logan, R. P. & Walker, M. M. ABC of the upper gastrointestinal tract: Epidemiology and diagnosis of Helicobacter pylori infection. BMJ 323, 920-922 (2001).


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T​he Foundation Years Clinical Cases Database is​ a selection of 600 peer-reviewed clinical cases in the field of patient safety and clinical practice, specifically focused on the clinical information needs of junior doctors, based around the Foundation Year Curriculum programme (MMC). The cases have been chosen to align with the Foundation Year Curriculum.

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