Clinical Case Database / Category: Clinical Care
Secondary prevention after MI
Publication details
Jessica Webb, Laura Cochrane, Pitt O Lim
Foundation Years Journal, volume 3, issue 2, p.14 (123Doc Education, London, March 2009)
Abstract
A 40-year-old lorry driver presented to the Emergency Department an hour after onset of central chest pain. He was a smoker with a family history of coronary artery disease. His 12 lead electrocardiogram confirmed an acute anterolateral ST elevation myocardial infarction (STEMI). Following intravenous morphine for analgesia and anti-emetics, he underwent immediate primary percutaneous coronary intervention (PCI) with preoperative loading doses of aspirin and clopidogrel, as well as an intravenous bolus dose of heparin.
Access the Clinical Cases Database
A subscription is required to read the full article. Please subscribe using one of the options below.
Product | Price | Subscription | |
---|---|---|---|
Foundation Years Clinical Cases Database | £29.00 | 6 months | |
Foundation Years Clinical Cases Database | £39.00 | 12 months |
Authors
Jessica Webb
Department of Cardiology
St George's Hospital
London
Laura Cochrane
Department of Cardiology
St George's Hospital
London
Pitt O Lim
Department of Cardiology
St George's Hospital
London
pitt.lim@stgeorges.nhs.uk
References
1. WHO, Death Rates from CHD, Men and Women Aged 35-74, Selected Countries. (http://www.who.int/cardiovascular_diseases/en/) 2007.
2. BHF, Incidence of Myocardial Infarction. (http://www.heartstats.org/ homepage.asp) 2008.
3. Bowker TJ, et al. A British Cardiac Society survey of the potential for the secondary prevention of coronary disease: ASPIRE (Action on Secondary Prevention through Intervention to Reduce Events). Heart, 1996, 75(4):334–342.
4. Randomised trial of intravenous streptokinase, oral aspirin, both, or neither among 17,187 cases of suspected acute myocardial infarction: ISIS-2. ISIS-2 (Second International Study of Infarct Survival) Collaborative Group. Lancet, 1988, 2(8607):349–360.
5. Baigent C, Collins R, Peto R. Article makes simple errors and could cause unnecessary deaths. BMJ, 2002, 324(7330):167.
6. Yusuf S, et al. Effects of clopidogrel in addition to aspirin in patients with acute coronary syndromes without ST-segment elevation. N Engl J Med, 2001, 345(7):494–502.
7. Mehta SR, et al. Effects of pretreatment with clopidogrel and aspirin followed by long-term therapy in patients undergoing percutaneous coronary intervention: the PCI-CURE study. Lancet, 2001, 358(9281):527–533.
8. Randomised trial of cholesterol lowering in 4,444 patients with coronary heart disease: the Scandinavian Simvastatin Survival Study (4S). Lancet, 1994, 344(8934):1383–1389.
9. MRC/BHF Heart Protection Study of cholesterol lowering with simvastatin in 20,536 high-risk individuals: a randomised placebo-controlled trial. Lancet, 2002, 360(9326):7–22.
10. Randomised trial of intravenous atenolol among 16,027 cases of suspected acute myocardial infarction: ISIS-1. First International Study of Infarct Survival Collaborative Group. Lancet, 1986, 2(8498):57–66.
11. Yusuf S, et al. Beta blockade during and after myocardial infarction: an overview of the randomised trials. Prog Cardiovasc Dis, 1985, 27(5):335–371.
12. NICE, Secondary prevention Post MI 2007.
13. ISIS-4: a randomised factorial trial assessing early oral captopril, oral mononitrate, and intravenous magnesium sulphate in 58,050 patients with suspected acute myocardial infarction. ISIS-4 (Fourth International Study of Infarct Survival) Collaborative Group. Lancet, 1995, 345(8951):669–685.
14. Dietary supplementation with n-3 polyunsaturated fatty acids and vitamin E after myocardial infarction: results of the GISSI-Prevenzione trial. Gruppo Italiano per lo Studio della Sopravvivenza nell'Infarto miocardico. Lancet, 1999, 354(9177):447–455.
15. Tan LB, Murphy R. Shifts in mortality curves: saving or extending lives? Lancet, 1999, 354(9187):1378–1381.16. Prasad A, Rihal C, Holmes DR Jr. The COURAGE trial in perspective. Catheter Cardiovasc Interv, 2008, 72(1):54–59.
17. Erne P, et al. Effects of percutaneous coronary interventions in silent ischemia after myocardial infarction: the SWISSI II randomised controlled trial. JAMA, 2007, 297(18):1985–1991.
18. Critchley JA, Capewell S. Mortality risk reduction associated with smoking cessation in patients with coronary heart disease: a systematic review. Jama, 2003, 290(1):86–97.
Disclaimers
Conflict Of Interest
The Journal requires that authors disclose any potential conflict of interest that they may have. This is clearly stated in the Journal’s published “Guidelines for Authors”. The Journal follows the Guidelines against Conflict of Interest published in the Uniform Requirements for Manuscripts Submitted to Biomedical Journals (http://www.icmje.org/urm_full.pdf).
Financial Statement
The authors of this article have not been paid. The Journal is financed by subscriptions and advertising. The Journal does not receive money from any other sources. The decision to accept or refuse this article for publication was free from financial considerations and was solely the responsibility of the Editorial Panel and Editor-in-Chief.
Patient Consent statement
All pictures and investigations shown in this article are shown with the patients’ consent. We require Authors to maintain patients’ anonymity and to obtain consent to report investigations and pictures involving human subjects when anonymity may be compromised. The Journal follows the Guidelines of the Uniform Requirements for Manuscripts (http://www.icmje.org/urm_full.pdf). The Journal requires in its Guidelines for Authors a statement from Authors that “the subject gave informed consent”.
Animal & Human Rights
When reporting experiments on human subjects, the Journal requires authors to indicate whether the procedures followed were in accordance with the ethical standards of the responsible committee on human experimentation (institutional and national) and with the HelsinkiDeclaration of 1975, as revised in 2008.
About the Clinical Cases Database
The Foundation Years Clinical Cases Database is a selection of 600 peer-reviewed clinical cases in the field of patient safety and clinical practice, specifically focused on the clinical information needs of junior doctors, based around the Foundation Year Curriculum programme (MMC). The cases have been chosen to align with the Foundation Year Curriculum.
The database is fully searchable, or can be browsed by medical specialty. Abstracts can be read free of charge, however a subscription is required in order to read the complete cases.