Clinical Case Database / Category: Patient Management

Post-transplant lymphoproliferative disease

Publication details

Dr Issaam Oozeerally, Dr Jonathan Barratt
Foundation Years Journal, volume 9, issue 5, p.38 (123Doc Education, London, May 2015)


Organ transplantation is one of the pillars of modern medicine. The increasing success of organ transplantation means the chances of Foundation doctors encountering a patient with a transplant on the acute medical or surgical take have never been higher. The immunosuppression used in transplantation increases the risk of developing a wide range of infectious complications. Post-transplant lymphoproliferative disorder (PTLD) is an important post-transplant complication that Foundation doctors should be aware of. In the vast majority of cases PTLD is caused by the Epstein-Barr Virus (EBV). We present a case of EBV-driven PTLD complicating renal transplantation followed by a brief overview of PTLD.

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Dr Issaam Oozeerally

John Walls Renal Unit
Leicester General Hospital
Gwendolen Road
Leicester, LE5 4PW

Dr Jonathan Barratt (Corresponding author)

John Walls Renal Unit
Leicester General Hospital
Gwendolen Road
Leicester, LE5 4PW


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T​he Foundation Years Clinical Cases Database is​ a selection of 600 peer-reviewed clinical cases in the field of patient safety and clinical practice, specifically focused on the clinical information needs of junior doctors, based around the Foundation Year Curriculum programme (MMC). The cases have been chosen to align with the Foundation Year Curriculum.

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