Clinical Case Database / Category: Patient Management

Positive effects of low-dose immunotherapy in a rheumatoid arthritis patient

Publication details

P Bajaj
Foundation Years Journal, volume 7, issue 8, p.22 (123Doc Education, London, August 2013)


Rheumatoid arthritis is an autoimmune systemic disease of unknown aetiology involving chronic polyarthritis and affects 2% of the economically active population. This paper discusses the case of a 39-year-old woman who presented with particular flaring-up of her arthritis at ovulation and in the second half of her menstrual cycle when oestrogen levels are high. At these times she became very fatigued, trembled internally, became easily confused and overtired, and had an acute reaction with uncontrollable muscle twitch and spasm. She also felt very nauseated and her limbs became weak. The patient was managed by low-dose immunotherapy (LDI) desensitising her for oestrogen, aerobic and anaerobic bacteria. The patient also switched over to a progesterone-only pill in an attempt to override her hormonal cycle and suppress ovulation. Desensitisation with LDI and self-vaccination treatment brought back the patient’s energy, calmed her stomach and improved her arthritis.

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P Bajaj

Medical Director
Modern Health Ltd
114 Kingshill Avenue


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T​he Foundation Years Clinical Cases Database is​ a selection of 600 peer-reviewed clinical cases in the field of patient safety and clinical practice, specifically focused on the clinical information needs of junior doctors, based around the Foundation Year Curriculum programme (MMC). The cases have been chosen to align with the Foundation Year Curriculum.

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