Clinical Case Database / Category: Clinical Care

Polycystic ovarian syndrome

Publication details

Dr Mandeep Kaler, Amita Mahendru MRCOG MD, Mr M A Khaled FRCOG PhD
Foundation Years Journal, volume 3, issue 3, p.58 (123Doc Education, London, April 2009)


Polycystic ovarian syndrome (PCOS) is a common disorder, often complicated by anovulatory infertility and hyperandrogenism, with the clinical manifestation of oligomenorrhoea, hirsutism and acne. Most clinical data suggests a prevalence of 6–7% of the population, with the highest incidence among South Asian women in the UK. Many women with this condition are obese and there is a higher incidence of impaired glucose tolerance, type 2 diabetes and sleep apnoea, than is observed in the general population (1). These cases can present for the first time to gynaecology, endocrinology, reproductive medicine, dermatology, diabetes, general practice, cardiovascular medicine and metabolic medicine.

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Dr Mandeep Kaler

Foundation year 2
Obstetrics and Gynaecology
Colchester Hospital University Foundation Trust
Turner Road
Colchester CO45JL

Amita Mahendru MRCOG MD

Specialist registrar
Obstetrics and Gynaecology
Colchester Hospital University Foundation Trust
Turner Road
Colchester CO4 5J

Mr M A Khaled FRCOG PhD

Consultant Gynaecologist and Director of Medical Education
Colchester Hospital University Foundation Trust
Turner Road
Colchester CO4 5JL


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2. Human reproduction. 2004, 19:41–47.
3. Fertility & Sterility, 2004, 81:19–25.
4. 2009.
5. Cho LW, Atkin SL. Management of polycystic ovarian syndrome. Trends in Urology Gynaecology & Sexual Health, 2008, 13:14–19.
6. Balen A. The current understanding of polycystic ovary syndrome. The obstetrician and gynaecologist, 2004, 6:66–74.
7. Sinha A, Atioma W. The role of metformin in the treatment of infertile women with polycystic ovary syndrome. The obstetrician and gynaecologist, 2004, 6:145–151.
8. Balen A. Surgical management of polycystic ovary syndrome: Pros and cons. The obstetrician and gynaecologist, 2000, 2:17–20.


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T​he Foundation Years Clinical Cases Database is​ a selection of 600 peer-reviewed clinical cases in the field of patient safety and clinical practice, specifically focused on the clinical information needs of junior doctors, based around the Foundation Year Curriculum programme (MMC). The cases have been chosen to align with the Foundation Year Curriculum.

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