Clinical Case Database / Category: Patient Management

Pancytopenia: a case of hairy cell leukaemia

Publication details

Dr Isabella S L Lo, Dr Alison E Milne
Foundation Years Journal, volume 9, issue 3, p.64 (123Doc Education, London, March 2015)


Pancytopenia is a common presentation to our day-to-day clinical practice. The causes of pancytopenia are diverse and severe pancytopenia can be life threatening therefore warrant urgent assessment and treatment. In this article, we described a case of pancytopenia caused by a rare form of leukaemia, hairy cell leukaemia, and illustrated a step-to-step approach leading to the diagnosis.

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Dr Isabella S L Lo

Haematology Department
North Hampshire Hospital, Basingstoke, Hampshire, RG24 9NA

Dr Alison E Milne (Corresponding author)

Haematology Department
North Hampshire Hospital, Basingstoke, Hampshire, RG24 9NA


1. Jones G, Parry-Jones N, Wilkins B, Else M, Catovsky D. Revised guidelines for the diagnosis and management of hairy cell leukaemia and hairy cell leukaemia variant*. British Journal of Haematology. 2012;156(2):186-95.
2. Tiacci E, Trifonov V, Schiavoni G, Holmes A, Kern W, Martelli MP, et al. BRAF Mutations in Hairy-Cell Leukemia. New England Journal of Medicine. 2011;364(24):2305-15.


Conflict Of Interest

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Financial Statement

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Patient Consent statement

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About the Clinical Cases Database

T​he Foundation Years Clinical Cases Database is​ a selection of 600 peer-reviewed clinical cases in the field of patient safety and clinical practice, specifically focused on the clinical information needs of junior doctors, based around the Foundation Year Curriculum programme (MMC). The cases have been chosen to align with the Foundation Year Curriculum.

The database is fully searchable, or can be browsed by medical specialty. Abstracts can be read free of charge, however a subscription is required in order to read the complete cases.