Clinical Case Database / Category: Case Based Discussion

Ocular complications of marfans & surgical management

Publication details

A Stuart
Foundation Years Journal, volume 7, issue 3, p.20 (123Doc Education, London, March 2013)


Our patient was a 19 year old girl who had a long standing diagnosis of Marfans syndrome. She was myopic and this was corrected with spectacle lenses. She presented to our eye clinic with a two month history of gradually worsening vision in both eyes. On examination she was found to have significantly subluxed lenses in both eyes (ectopia lentis). Dilated fundoscopy revealed normal retinas in both eyes. She was subsequently listed for right lensectomy and anterior chamber lens insertion (to be later followed by the same procedure in the left eye).

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A Stuart



1. Ectopia lentis as the presenting and primary feature in Marfan’s syndrome (Zadeh et al American journal of medical genetics 2011)
2. Marfan syndrome; Clinical diagnosis and management. (Dean JC European journal of human genetics 2007)
3. Combined pars-plana lensectomy-vitrectomy with open-loop flexible anterior chamber intra-ocular lens (AC-IOL) implantation for subluxed lens (Kazemi et al Trans am Ophthal Soc 2000)
4. Combined pars-plana vitrectomy and sutured posterior chamber implant (Johnston et al Arch of Ophthal 2000)
5. Scleral suspension pars-plana lensectomy for ectopia lentis followed by suture fixation of intraocular lens (Mitra et al Indian J Ophthal 2001)
6. Artisian iris-claw lenses for the correction of aphakia in children following lensectomy for ectopia lentis (Cleary et al British Journal of Ophthalmology 2011).


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T​he Foundation Years Clinical Cases Database is​ a selection of 600 peer-reviewed clinical cases in the field of patient safety and clinical practice, specifically focused on the clinical information needs of junior doctors, based around the Foundation Year Curriculum programme (MMC). The cases have been chosen to align with the Foundation Year Curriculum.

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