Clinical Case Database / Category: Patient Management

Diagnosis and management of a patient with inflammatory myopathy

Publication details

Dr Matt Popplewell, Dr Diarmuid Mulherin
Foundation Years Journal, volume 6, issue 2, p.25 (123Doc Education, London, February 2012)

Abstract

We present a case of polymyositis associated with extra-muscular involvement of the lungs and oesophagus. This case discussion highlights the importance of diagnosis and treatment. Early diagnosis of the disease is important, as it is associated with high mortality and morbidity. The aetiology of inflammatory myopathy is poorly understood. However successful treatment with corticosteroids and disease modifying agents can greatly improve quality of life and reduce relapses of the disease.

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Authors

Dr Matt Popplewell

-

Dr Diarmuid Mulherin

Consultant Rheumatologist,
Department Of Rheumatology,
Cannock Chase Hospital,
Cannock, WS11 5XY
diarmuid.mulherin@midstaffs.nhs.uk

References

1. Wortmann R. Inflammatory diseases of muscle and other myopathies. In: Harris E, Budd R, Firestein G, et al. editors. Kelley’s Textbook of Rheumatology. 7th ed. Philadelphia: Elsevier Saunders 2005; 1309-35.
2. Murthy JNK. Drug treatment of polymyositis and dermatomyositis. Neurology India 2010; 58:1 3-5.
3. Lundberg IE, Vencovsky J. Polymyositis, Dermatomyositis. Inflammatory diseases of muscle and other myopathies. Eular on-line course on Connective Tissue Diseases 2007; 7:1-43.
4. Bohan A, Peter JB. Polymyositis and dermatomyositis (first of two parts). N Engl J Med 1975;292(7):344-7.
5. Bakewell CJ, Raghu G. Polymyositis associated with severe interstitial lung disease: Remission after three doses of IV immunoglobulin. Chest 2011; 139(2).
6. Bohan A, Peter JB, Bowman RL, Pearson CM. A computer-assisted analysis of 153 patients with polymyositis and dermatomyositis. Medicine 1977; 86:255-86.
7. Henriksson KG, Lindvall B. Polymmyositis and dermatomyositis 1990-diagnosis, treatment and prognosis. Prog Neurobiol 1990;35: 181-93.
8. Danko K, Pnyi A, Constantin T, Borgulya G, Szegedi G. Long-term survival of patients with idiopathic inflammatory myopathies according to clinical features: A longitudinal study of 162 cases. Medicine (Baltimore) 2004;83:35-42.

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Conflict Of Interest

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About the Clinical Cases Database

T​he Foundation Years Clinical Cases Database is​ a selection of 600 peer-reviewed clinical cases in the field of patient safety and clinical practice, specifically focused on the clinical information needs of junior doctors, based around the Foundation Year Curriculum programme (MMC). The cases have been chosen to align with the Foundation Year Curriculum.

The database is fully searchable, or can be browsed by medical specialty. Abstracts can be read free of charge, however a subscription is required in order to read the complete cases.