Clinical Case Database / Category: Case Based Discussion

Common oncological emergencies

Publication details

Dr Eliyaz Ahamed PhD, MRCP, Professor Mark Bower PhD, FRCP, FRCPath
Foundation Years Journal, volume 4, issue 4, p.5 (123Doc Education, London, April 2010)


You are an SHO in A&E and asked to see a 70-year-old man with known metastatic prostate cancer stage T4NXM1, for which he is receiving anti-androgen therapy. Over the past month he has been complaining of mid-back pain that radiates around his chest when he coughs. This morning he got out of bed and his legs gave way. He also says that over the last week he has noticed increased urinary frequency and now has developed urinary incontinence.

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Dr Eliyaz Ahamed PhD, MRCP

Consultant Medical Oncologist at Clatterbridge Hospital
Chelsea and Westminster Hospital

Professor Mark Bower PhD, FRCP, FRCPath

Consultant Medical Oncologist
Chelsea and Westminster Hospital
369 Fulham Road
London SW10 9NH


1. Loblaw DA, et al. (2005) Systematic review of the diagnosis and management of malignant extradural spinal cord compression: the Cancer Care Ontario Practice Guidelines Initiative's Neuro-Oncology Disease Site Group. J Clin Oncol, 23(9):2028–2037.
2. Prasad D, Schiff D (2005) Malignant spinal-cord compression. Lancet Oncol, 6(1):15–24.
3. Rowell NP, Gleeson FV (2002) Steroids, radiotherapy, chemotherapy and stents for superior vena caval obstruction in carcinoma of the bronchus: a systematic review. Clin Oncol (R Coll Radiol), 14(5): 338–351.
4. Miller JH, et al. (2000) Malignant superior vena cava obstruction: stent placement via the subclavian route. Cardiovasc Intervent Radiol, 23(2):155–158.
5. Feusner JH, et al. (2008) Management of tumor lysis syndrome: need for evidence-based guidelines. J Clin Oncol, 26(34):5657–5658; author reply 5658–5659.
6. Tosi P, et al. (2008) Consensus conference on the management of tumor lysis syndrome. Haematologica, 93(12):1877–1885.
7. Hochberg J, Cairo MS (2008) Tumor lysis syndrome: current perspective. Haematologica, 93(1):9–13.
8. NICE (2008) Metastatic spinal cord compression. Diagnosis and management of adults at risk of and with metastatic spinal cord compression. NICE clinical guideline 75.


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About the Clinical Cases Database

T​he Foundation Years Clinical Cases Database is​ a selection of 600 peer-reviewed clinical cases in the field of patient safety and clinical practice, specifically focused on the clinical information needs of junior doctors, based around the Foundation Year Curriculum programme (MMC). The cases have been chosen to align with the Foundation Year Curriculum.

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