Clinical Case Database / Category: Patient Management

Clinical aspects of Lyme disease

Publication details

Tim Blake MBCHB, BSC (Physiology And Pharmacology), MRCP, Naveen Bhadauria, MBBS, BSC (Immunology)
Foundation Years Journal, volume 5, issue 7, p.17 (123Doc Education, London, August 2011)

Abstract

This article presents a brief history of a patient presenting in the early stage of Lyme disease, an emerging infectious disease in Europe. The reader is directed towards making a clinical diagnosis. Consideration should be given to rashes (including atypical ones), evolution of symptoms, investigations, treatment and prevention.

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Authors

Tim Blake MBCHB, BSC (Physiology And Pharmacology), MRCP

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Naveen Bhadauria, MBBS, BSC (Immunology)

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References

1. Imboden JB, Hellmann DB, Stone JH. Lyme disease. Current diagnosis and treatment in Rheumatology 2nd Edition. Lange/McGraw-Hill 2007; 48:3
2. Feder HM Jr. Lyme disease in children. Infect Dis Clin North Am. Jun 2008;22(2):315-26
3. British Infection Association. Journal of Infection 2011 62, 329-338
4. Hess A, Buchmann J, Zettl UK, et al. Borrelia burgdorferi central nervous system infection presenting as an organic schizophrenia-like disorder. Biol. Psychiatry 1999 45 (6): 795
5. http://emedicine.medscape.com/article/330178-overview
6. Health Protection Agency. An independent appraisal and review of ILADS 2004 'Evidence-based guidelines for the management of Lyme disease' (Professor BI Duerden, Chair). Report presented to HPA December 2010;8. Available at http://www.hpa.org.uk/Topics/InfectiousDiseases/InfectionsAZ/LymeDisease/General Information/; December 2010
7. Brouqui, P., Bacellar, F., Baranton, G. et al. Guidelines for the diagnosis of tick-borne bacterial diseases in Europe. Clinical Microbiology and Infectious Diseases 2004 10(12), 1108-1132
8. Wormser, G.P., Dattwyler, R.J., Shapiro, E.D. et al. The clinical assessment, treatment and prevention of Lyme disease, human granulocytic anaplasmosis, and babesiosis: clinical practice guidelines by the Infectious Diseases Society of America. Clinical Infectious Diseases 2006 43(9), 1089-1134
9. Mygland A, Ljøstad U, Fingerle V, Rupprecht T, Schmutzhard E, Steiner I. European Federation of Neurological Societies guidelines on the diagnosis and management of European Lyme neuroborreliosis. European Journal of Neurology 2010 17:8-16
10. Sood SK, Salzman MB, Johnson BJ, Happ CM, Feig K, Carmody L, et al. Duration of tick attachment as a predictor of the risk of Lyme disease in an area in which Lyme disease is endemic. J Infect Dis 1997;175(4):996-9
11. Nadelman et al. Prophylaxis with single-dose doxycycline for the prevention of Lyme disease after an Ixodes scapularis tick bite. N Engl J Med. 2001 345(2):79-84

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T​he Foundation Years Clinical Cases Database is​ a selection of 600 peer-reviewed clinical cases in the field of patient safety and clinical practice, specifically focused on the clinical information needs of junior doctors, based around the Foundation Year Curriculum programme (MMC). The cases have been chosen to align with the Foundation Year Curriculum.

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