Clinical Case Database / Category: Patient Management

Choroidal granuloma: a case of ocular tuberculosis

Publication details

Mr. Michail Katzakis MD, FEBO, Dr Phil GF Raines FRCP, Miss Sudeshna Patra, FRCS (ophth)
Foundation Years Journal, volume 9, issue 6, p.14 (123Doc Education, London, June 2015)

Abstract

Ocular tuberculosis (TB) is a rare manifestation of extrapulmonary TB. We present the case of a 21-year-old female South Asian patient with systemic TB who developed choroidal granulomas in the left eye. Following successful treatment with anti-TB therapy the granulomas resolved forming chorioretinal scars. However, this was complicated by the development of a choroidal neovascular membrane (CNVM) at the site of the scar one year later.

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Authors

Mr. Michail Katzakis MD, FEBO

Senior Clinical Fellow in Ophthalmology
Eye Treatment Centre
Whipps Cross University Hospital
Whipps Cross Road
Leytonstone, London, E11 1NR
mkatzakis@gmail.com

Dr Phil GF Raines FRCP

Consultant Respiratory Physician
Chest Clinic
Whipps Cross University Hospital
Whipps Cross Road
Leytonstone, London, E11 1NR
phil.raines@bartshealth.nhs.uk

Miss Sudeshna Patra, FRCS (ophth) (Corresponding author)

Consultant Ophthalmic Surgeon
Eye Treatment Centre
Whipps Cross University Hospital
Whipps Cross Road
Leytonstone

References

1. Fonseca JD, Knight GM, McHugh TD. The complex evolution of antibiotic resistance in Mycobacterium tuberculosis. International Journal of Infectious Diseases. 2015;32:94-100
2. Gupta A, Gupta V. Tubercular posterior uveitis. Int Ophthal Clin. 2005;45(2):71-88
3. Gupta V, Shoughy SS, Mahajan S. et al. Clinics of Ocular Tuberculosis. Ocular Immunology & Inflammation. 2015;23(1):14-24
4. Samson MC, Foster CS. Tuberculosis. In: Foster CS, Vitale AT eds. Diagnosis and Treatment of Uveitis. W.B. Saunders 2002 pg. 264-271
5. Gupta A, Bansal R, Gupta V, Sharma A, Bambery P. Ocular Signs Predictive of Tubercular Uveitis. Am J Ophthalmol. 2010;149:562-570
6. Agrawal R, Gupta B, Gonzalez-Lopez JJ et al. The Role of Anti-tubercular Therapy in Patients with Presumed Ocular Tuberculosis. Ocular Immunology & Inflammation. 2015;23(1):40-46
7. Basu S, Das T. Pitfalls in the management of TB-associated uveitis. Eye. 2010;24:1681-1684
8. Julian K, Terrada C, Fardeau C et al. Intravitreal bevacizumab as first local treatment for uveitis-related choroidal neovascularization: long-term results. Acta Ophthalmol. 2011;89:179-184
9. Chung YM, Yeh TS, Sheu SJ, Liu JH. Macular

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T​he Foundation Years Clinical Cases Database is​ a selection of 600 peer-reviewed clinical cases in the field of patient safety and clinical practice, specifically focused on the clinical information needs of junior doctors, based around the Foundation Year Curriculum programme (MMC). The cases have been chosen to align with the Foundation Year Curriculum.

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