Clinical Case Database / Category: Case Based Discussion
Alcoholic liver disease
Publication details
Philip SJ Hall MB BCh BAO (Hons), Ian Carl MPhil MRCP (Edin), Neil I McDougall MD FRCP (Edin), W. Jonathan Cash MD MRCP
Foundation Years Journal, volume 5, issue 8, p.55 (123Doc Education, London, September 2011)
Abstract
This case based discussion follows the clinical course of a 42 year old man who drinks alcohol to excess and presents with deranged liver tests. It will focus on the assessment and diagnosis of liver disease caused by alcohol misuse and the management of clinical problems related to this disease process.
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Authors
Philip SJ Hall MB BCh BAO (Hons)
SHO Gastroenterology
The Liver Unit, Royal Victoria Hospital, Belfast
Ian Carl MPhil MRCP (Edin)
Gastroenterology SPR
The Liver Unit, Royal Victoria Hospital, Belfast
Neil I McDougall MD FRCP (Edin)
Consultant Gastroenterologist and Hepatologist
The Liver Unit, Royal Victoria Hospital, Belfast
W. Jonathan Cash MD MRCP
Consultant Gastroenterologist and Hepatologist
The Liver Unit, Royal Victoria Hospital, Belfast
Johnny.cash@belfasttrust.hscni.net
References
1. Alcohol use disorders: physical complications. NICE guidelines 2010.
2. Stranges S, Freudenheim JL, Muti P, Farinaro E, Russell M, Nochajski TH et al. Differential effects of alcohol drinking pattern on liver enzymes in men and women. Alcohol Clin.Exp.Res. 2004;28:949-56.
3. Moussavian SN, Becker RC, Piepmeyer JL, Mezey E, Bozian RC. Serum gamma-glutamyl transpeptidase and chronic alcoholism. Influence of alcohol ingestion and liver disease. Dig.Dis.Sci. 1985;30:211-4.
4. McCullough AJ. Update on nonalcoholic fatty liver disease. J.Clin. Gastroenterol. 2002;34:255-62.
5. Marsano LS, Mendez C, Hill D, Barve S, McClain CJ. Diagnosis and treatment of alcoholic liver disease and its complications. Alcohol Res. Health 2003;27:247-56.
6. Maddrey WC, Boitnott JK, Bedine MS, Weber FL, Jr., Mezey E, White RI, Jr. Corticosteroid therapy of alcoholic hepatitis. Gastroenterology 1978;75:193-9.
7. Forrest EH, Morris AJ, Stewart S, Phillips M, Oo YH, Fisher NC et al. The Glasgow alcoholic hepatitis score identifies patients who may benefit from corticosteroids. Gut 2007;56:1743-6.
8. Grant A NJDCSS. Guidelines on the use of Liver Biospy in Clinical Practice. British Society of Gastroenterology. http://www.bsg.org.uk/images/stories/docs/clinical/guidelines/liver/liver_biopsy.pdf 2004.
9. O'Shea RS, Dasarathy S, McCullough AJ. Alcoholic liver disease. Hepatology 2010;51:307-28.
10. Martinez SM, Crespo G, Navasa M, Forns X. Noninvasive assessment of liver fibrosis. Hepatology 2011;53:325-35.
11. Foucher J, Chanteloup E, Vergniol J, Castera L, Le Bail B, Adhoute X et al. Diagnosis of cirrhosis by transient elastography (FibroScan): a prospective study. Gut 2006;55:403-8.
12. Mueller S, Millonig G, Sarovska L, Friedrich S, Reimann FM, Pritsch M et al. Increased liver stiffness in alcoholic liver disease: differentiating fibrosis from steatohepatitis. World J.Gastroenterol. 2010;16:966-72.
13. Runyon BA. Management of adult patients with ascites due to cirrhosis. Hepatology 2004;39:841-56.
14. EASL clinical practice guidelines on the management of ascites, spontaneous bacterial peritonitis, and hepatorenal syndrome in cirrhosis. J.Hepatol. 2010;53:397-417.
15. Ponziani FR, Zocco MA, Campanale C, Rinninella E, Tortora A, Di Maurizio L et al. Portal vein thrombosis: insight into physiopathology, diagnosis, and treatment. World J.Gastroenterol. 2010;16:143-55.
16. Garcia-Tsao G, Sanyal AJ, Grace ND, Carey WD. Prevention and management of gastroesophageal varices and variceal hemorrhage in cirrhosis. Am.J.Gastroenterol. 2007;102:2086-102.
17. Soares-Weiser K, Brezis M, Tur-Kaspa R, Paul M, Yahav J, Leibovici L. Antibiotic prophylaxis of bacterial infections in cirrhotic inpatients: a meta-analysis of randomized controlled trials. Scand.J.Gastroenterol. 2003;38:193-200.
18. Scottish Intercollegiate Guidelines Network. Management of acute upper and lower gastrointestinal bleeding. A national clinical guideline. SIGN guidelines 2009.
19. Thomson AD, Bird GL, Saunders JB. Alcoholic liver disease. Gut 1991;Suppl:S97-103.
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The Foundation Years Clinical Cases Database is a selection of 600 peer-reviewed clinical cases in the field of patient safety and clinical practice, specifically focused on the clinical information needs of junior doctors, based around the Foundation Year Curriculum programme (MMC). The cases have been chosen to align with the Foundation Year Curriculum.
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