Clinical Case Database / Category: Patient Management
Acute severe ulcerative colitis
Publication details
Simon TC Peake MBBS, BSc, MRCP, Jonathan Landy MBCHB, BMedSci, MRCP, Ailsa L Hart BMBCh MRCP PhD
Foundation Years Journal, volume 5, issue 8, p.31 (123Doc Education, London, September 2011)
Abstract
Acute severe ulcerative colitis will affect 15% of UC patients at some point in their disease course.1 Twenty percent of first attacks of UC are 'acute severe' in nature (1). The goal of medical therapy is to avoid colectomy, while preventing complications of disease, side effects of medications and mortality. In addition to medical therapies, optimisation of the overall supportive care of patients with acute severe UC is essential. In this article we present a typical case of acute severe UC presenting on a general medical take. The case has been used to illustrate the diagnosis, investigations and immediate management of a patient with acute severe UC.
Access the Clinical Cases Database
A subscription is required to read the full article. Please subscribe using one of the options below.
| Product | Price | Subscription | |
|---|---|---|---|
| Foundation Years Clinical Cases Database | £29.00 | 6 months | |
| Foundation Years Clinical Cases Database | £39.00 | 12 months |
Authors
Simon TC Peake MBBS, BSc, MRCP
Inflammatory Bowel Disease Clinical Fellow
St Mark's Hospital
simon.peake@nwlh.nhs.uk
Jonathan Landy MBCHB, BMedSci, MRCP
Inflammatory Bowel Disease Research Fellow
St Mark's Hospital
Ailsa L Hart BMBCh MRCP PhD
Consultant Gastroenterologist and Lead of IBD Unit
St Mark's Hospital and Senior Clinical Lecturer
Imperial College London
ailsa.hart@nwlh.nhs.uk
References
1. Edwards FC, Truelove SC. The course and prognosis of ulcerative colitis. Gut 1963; 4:299-315.
2. Truelove SC, Witts LJ. Cortisone in ulcerative colitis; preliminary report on a therapeutic trial. Br Med J 1954; 2:375-378.
3. Travis SP, Farrant JM, Ricketts C, et al. Predicting outcome in severe ulcerative colitis. Gut 1996; 38:905-910.
4. Laharie D, Bourreille A, Branche J, et al. Cyclosporin versus Infliximab in severe acute ulcerative colitis refractory to intravenous steroids: A randomised study. JCC 2011; 5(1):58.
Disclaimers
Conflict Of Interest
The Journal requires that authors disclose any potential conflict of interest that they may have. This is clearly stated in the Journal’s published “Guidelines for Authors”. The Journal follows the Guidelines against Conflict of Interest published in the Uniform Requirements for Manuscripts Submitted to Biomedical Journals (http://www.icmje.org/urm_full.pdf).
Financial Statement
The authors of this article have not been paid. The Journal is financed by subscriptions and advertising. The Journal does not receive money from any other sources. The decision to accept or refuse this article for publication was free from financial considerations and was solely the responsibility of the Editorial Panel and Editor-in-Chief.
Patient Consent statement
All pictures and investigations shown in this article are shown with the patients’ consent. We require Authors to maintain patients’ anonymity and to obtain consent to report investigations and pictures involving human subjects when anonymity may be compromised. The Journal follows the Guidelines of the Uniform Requirements for Manuscripts (http://www.icmje.org/urm_full.pdf). The Journal requires in its Guidelines for Authors a statement from Authors that “the subject gave informed consent”.
Animal & Human Rights
When reporting experiments on human subjects, the Journal requires authors to indicate whether the procedures followed were in accordance with the ethical standards of the responsible committee on human experimentation (institutional and national) and with the HelsinkiDeclaration of 1975, as revised in 2008.
About the Clinical Cases Database
The Foundation Years Clinical Cases Database is a selection of 600 peer-reviewed clinical cases in the field of patient safety and clinical practice, specifically focused on the clinical information needs of junior doctors, based around the Foundation Year Curriculum programme (MMC). The cases have been chosen to align with the Foundation Year Curriculum.
The database is fully searchable, or can be browsed by medical specialty. Abstracts can be read free of charge, however a subscription is required in order to read the complete cases.