Clinical Case Database / Category: Clinical Care

Acute kidney injury (AKI) - diagnosis, investigation and management

Publication details

Dr Nicholas Hobbs, Dr Kim Sinnamon, Dr Meryl Griffiths
Foundation Years Journal, volume 8, issue 4, p.6 (123Doc Education, London, April 2014)


Around 20% of hospitalised patients develop AKI (1). The NCEPOD (National Confidential Enquiry into Patient Outcome and Death) review of patients who died in hospital with AKI reported that only around 50% of patients received (what they determined as) good AKI management (2). It is vital to understand how to diagnose, investigate and manage AKI appropriately in order to lessen the high morbidity and mortality associated with this condition.

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Dr Nicholas Hobbs

Colchester Hospital University NHS Foundation Trust
Colchester General Hospital
Trust Offices, Main Building
Turner Road, Colchester
Essex, CO4 5JL

Dr Kim Sinnamon

Colchester Hospital University NHS Foundation Trust
Renal Unit
Primary Care Centre
Turner Road

Dr Meryl Griffiths

Cambridge University Hospitals NHS Foundation Trust
Hills Road
Cambridge, CB2 0QQ


1. Bellomo R, Kellum JA, Ronco C. Acute Kidney Injury. The Lancet, 2012 Aug;25:380(9843):756-66
2. NCEPOD report: AKI Adding Insult to Injury, June 2009
3. KDIGO Clinical Practice Guideline for Acute Kidney Injury. Kidney International Supplements 2012 Mar;2(1):1-138.


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About the Clinical Cases Database

T​he Foundation Years Clinical Cases Database is​ a selection of 600 peer-reviewed clinical cases in the field of patient safety and clinical practice, specifically focused on the clinical information needs of junior doctors, based around the Foundation Year Curriculum programme (MMC). The cases have been chosen to align with the Foundation Year Curriculum.

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